Bond teams up with a government agent named Camille to stop Greene and dig up clues on Quantum and its leader, Mr. Greene has been siphoning Bolivia's water and oil supply with help from the corrupt general Madrano. Bond's investigation leads him to Dominic Greene, a businessman with ties to Quantum. His deceased lover, Vesper Lynd, had ties to the group, and he's trying to figure out what they're up to. Loosely based on the film of the same name, the game follows James Bond, who is on the hunt for members of a clandestine organization called Quantum. The same year, Activision picked up the rights to 007, and would release their first title, Quantum of Solace, in 2008. In 2006, James Bond returned to cinemas with Casino Royale, a reboot which focused on a younger, lesser-experienced Bond, and had a grittier tone compared to previous outings.

Meanwhile, the financial failure of Goldeneye: Rogue Agent and From Russia With Love led to EA losing the rights.

The film didn't do well critically and while it was a financial hit, fans didn't appreciate how absurd James Bond had gotten. 2002's Die Another Day left the 007 series at the crossroads.